The IOTLab of the Politecnico di Milano, led by Giovanni Miragliotta and Antonio Capone, scientific managers, with the 9 partner companies representatives, presented the results of the Open Lab Smart Home project aimed at building an smart home ecosystem consisting of multi vendors interoperable devices able to meet user needs and habits. A major stop to the massive spread of Smart Home solutions in Italy remains the incommunicability among the many existing solutions and the lack of interoperability: the different applications the user is required to install on his/her smartphone to control each device cannot talk to each other preventing Smart Home from being fully convincing in terms of usability and simplicity. The Open Lab Smart Home project involves Smart Home market main players such as Bticino, Epta, Ezviz, Gewiss, Signify, SoloMio, Beeta by Tera, Vimar and V by Vodafone who cover different roles in the value chain, from device manufacturers to system integrators, passing through service providers. Through the creation of 6 use cases related to different areas (Safety, Comfort, Personal Assistance and Safety) the positive effects and potentialities conferred on the smart home by achieving interoperability among mono-vendor solutions have been demonstrated. The 6 use cases integrate different technological elements enabling open source platforms (for example Node-RED), protocols of Publish / Subscribe messaging (for example MQTT), API cloud interfaces of various devices and voice assistants (eg Amazon Alexa and Google Assistant).