NECSTFridayTalk – A Functional Data Analysis Approach to Left Ventricular Remodeling Assessment
NECSTFridayTalk
Letizia Clementi
DEIB PhD student
Event will be online from Facebook
October 29th, 2021
1.00 pm
Contacts:
Marco Santambrogio
Research Line:
System architectures
Letizia Clementi
DEIB PhD student
Event will be online from Facebook
October 29th, 2021
1.00 pm
Contacts:
Marco Santambrogio
Research Line:
System architectures
Abstract
On October 29th, 2021 at 1.00 pm "A Functional Data Analysis Approach to Left Ventricular Remodeling Assessment", a new appointment of NECSTFridayTalk, will be held online via Facebook by Letizia Clementi, DEIB PhD student in Data Analysis and Decision Science.
Left ventricular remodeling is a mechanism common to various cardiovascular diseases affecting myocardial morphology. It can be often overlooked in clinical practice since the parameters routinely employed in the diagnostic process (e.g., the ejection fraction) mainly focus on evaluating volumetric aspects. Nevertheless, the integration of a quantitative assessment of structural modifications can be pivotal in the early individuation of this pathology. In this work, we propose an approach based on functional data analysis to evaluate myocardial contractility. A functional representation of ventricular shape is introduced, and functional principal component analysis and depth measures are used to discriminate healthy subjects from those affected by left ventricular hypertrophy. Our approach enables the integration of higher informative content compared to the traditional clinical parameters, allowing for a synthetic representation of morphological changes in the myocardium, which could be further explored and considered for future clinical practice implementation.
Left ventricular remodeling is a mechanism common to various cardiovascular diseases affecting myocardial morphology. It can be often overlooked in clinical practice since the parameters routinely employed in the diagnostic process (e.g., the ejection fraction) mainly focus on evaluating volumetric aspects. Nevertheless, the integration of a quantitative assessment of structural modifications can be pivotal in the early individuation of this pathology. In this work, we propose an approach based on functional data analysis to evaluate myocardial contractility. A functional representation of ventricular shape is introduced, and functional principal component analysis and depth measures are used to discriminate healthy subjects from those affected by left ventricular hypertrophy. Our approach enables the integration of higher informative content compared to the traditional clinical parameters, allowing for a synthetic representation of morphological changes in the myocardium, which could be further explored and considered for future clinical practice implementation.
The NECSTLab is a DEIB laboratory, with different research lines on advanced topics in computing systems: from architectural characteristics, to hardware-software codesign methodologies, to security and dependability issues of complex system architectures.
Every week, the “NECSTFridayTalk” invites researchers, professionals or entrepreneurs to share their work experiences and projects they are implementing in the “Computing Systems”.
Streaming via Facebook will be available at the following link